HP ProDesk 400 G2.5 SFF vs. HP ProDesk 400 G6 SFF
Comparison and Differences
Differences between HP ProDesk 400 G2.5 SFF and HP ProDesk 400 G6 SFF
Both models have the same form factor, meaning reoughtly they have the same phiysical size and form.
Usually the newer the generation of the CPU, the better the performance and efficiency is. If your budget allows it, you should go with the HP ProDesk 400 G6 SFF as it is running a newer generation CPU. This is not to say that HP ProDesk 400 G2.5 SFF is bad - it can still run some powerful CPUs, albeit being an older generation.
Both models have have equal amount of ram slots (2 RAM). Usually two RAM slots are more than enough for most cases. However, the count should be taken into account when planning how much and what combination of RAM you are going to need for your system.
The HP ProDesk 400 G6 SFF is using the faster 2666 MT/s RAM. The HP ProDesk 400 G2.5 SFF is slower by supporting RAM speeds of up to 1600 MT/s. Additionally, if you will be needing a lot of RAM, better go for the HP ProDesk 400 G6 SFF as it has the ability to run 64 GB of RAM. The HP ProDesk 400 G2.5 SFF can do a bit less at max 16 GB. Most of the times, this should be sufficient for the majority of users.
Both models have the same amount of USB ports for total count of 8. If this is not enough, using a USB hub is always a viable option. None of the desktop models has a USB 3.1 port (10Gb/s), so if you need a fast connection to your peripherals, like external Solid State Drive, you will need to look elsewhere.
The DisplayPort is usually the more popular video port used with desktops and laptops, while the HDMI is used predominantly in consumer electronics. That's why, it is good to see that both of the models come with a DisplayPort.
None of the models has an HDMI port. If your monitor supports only the HDMI interface, you will need to buy an adapter. Such adapters are cheap so nothing to worry about.
SATA ports are placed on the system board and it is where you connect your HDD, SSD and Optical Disk Drives. More SATA slots will allow you to have more drives running at the same time. In this regard the HP ProDesk 400 G2.5 SFF is better equipped as it comes with 3 SATA slot(s), while the HP ProDesk 400 G6 SFF has 2 slot(s).
If you want the fastest transfer speeds for your SSD, an M.2 interface is crucial. Thus, if the M.2 SSD slot is a mandatory requirement for you, go with the HP ProDesk 400 G6 SFF. Sadly, the HP ProDesk 400 G2.5 SFF has no such slot, and you will be forced to use the SATA interface instead.
Make sure that the available M.2 slot supports the PCIe (also called NVMe) interface. This is important as there are M.2 slots which support only the inferior SATA III interface. For comparison, the SATA III interface has max speeds of 6Gb/s, while the PCIe 3.0 x4 will support speeds up to 32Gb/s!
Looking at the Power Supply Unit (PSU) of the two models we don't see any differences. For either of them you get a maximum power of 180 Watts. However be careful, many models have more than one power supply option. When buying your computer, it is a good idea to get a version with the most powerful PSU. This will potentially allow you to upgrade to a more powerful GPU for example.